Sickle Cell Disease

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In Process

Author / Curator:

Faculty Advisor:

GUIDELINES:
The format of each page are recommended guidelines. They should be fluid as each topic will have a unique flow.

(1) Be concise.

(2) Be evidence-based. (Everything should have a reputable citation and resource)

(3) Be clinically relevant. (Avoid unnecessary discussion of pathophysiology and epidemiology if it does not help clinical decision-making).


Top Teaching Points

Background

This portion should be a brief background. It may include recommended sub-headers:

- Epidemiology

- Physiology / Pathophysiology

- Progression and Complications of Disease (i.e. what we get worried about)

Diagnosis

All diagnosis information should be evidence-based only. Recommended sub-headers:

- Signs and Symptoms

- Differential Diagnosis (i.e. what else to look for)

- Physical Exam Findings

- Recommended Work-up (Evidence-based Labs / Imaging / Diagnostics)

Management

All treatment information should include citations and evidence-based links. Recommended sub-headers:

- Non-pharmalogical treatment

- Pharmacological treatments

- Things to Avoid (e.g. dietary, medication restrictions)

Other Teaching Pearls

These should be short one-liners (with citations) of unique or interesting "pearls" that can offer teaching points for more advanced practitioners. (e.g. Losartan is the only ARB hypertensive agent that is associated with a lower incidence of gout attacks [1])

Trial Summaries

These are brief one-line summaries of relevant trials and studies. One recommendation is to like to discussion pages like WikiJournalClub for further information.

Ongoing controversies / New updates

What's the latest scuttlebutt? This is a place to include new guidelines, controversies, or other recent updates on the topic.

Teaching Resources

Blogs:

Videos:

Podcast episodes:

Core review articles / Guidelines:

Other links:

References

Sickle Cell Disease
  1. Choi et al.: Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study. BMJ 2012;344:d8190.